With Donald Trump’s re-election as the 47th President of the United States, Washington’s role in the MENA region is poised for renewed scrutiny. While the incoming President is already well-acquainted with the region’s complex challenges and power dynamics from his previous term, his return coincides with heightened turmoil, marked by conflicts in Gaza and Lebanon. In this volatile context, shifts in US foreign policy toward the MENA region – particularly regarding the war in Gaza, the US-Israel alliance, and a potential recalibration of Washington’s approach toward Iran – could have great consequences for the regional actors and the US itself. What does Trump’s re-election mean for the MENA region? Will his second term bring a revival of past strategies, or will new realities on the ground demand a different approach? How might his administration reassess alliances and redefine priorities on critical issues such as regional security, economic interests, and diplomatic engagement?